Publications

The Chavkin Lab is new in 2024 and is actively working to fill this page - reach out if you want to help publish exciting new science!

Previous work by Dr. Chavkin that supports ongoing lab research:

2024

Horitani K*, Chavkin NW*, Arai Y, Wang Y, Ogawa H, Yura Y, Evans MA, Cochran J, Thel MC, Sano M, Miura-Yura E, Arai Y, Doviak H, Arnold AP, Hirschi KK, Sano S*, Walsh K. Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure. Nature Cardiovasc Res. 2024 Mar 8;3:343-355. *Co-first authors.

2023

Chavkin NW#, Vippa T, Jung C, McDonnell S, Hirschi KK, Gokce N, Walsh K#. Obesity accelerates endothelial-to-mesenchymal transition in adipose tissues of mice and humans. Front Cardiovasc Med. 2023 Sep 19;10:1264479. #Co-corresponding Authors

2022

Chavkin NW, Genet G, Poulet M, Jeffery ED, Marziano C, Genet N, Vasavada H, Nelson EA, Acharya BR, Kour A, Aragon J, McDonnell SP, Huba M, Sheynkman GM, Walsh K, Hirschi KK. Endothelial cell cycle state determines propensity for arterial-venous fate. Nat Commun. 2022 Oct 6;13(1):5891.

Sano S, Horitani K, Ogawa H, Halvardson J, Chavkin NW, Wang Y, Sano M, Mattisson J, Hata A, Danielsson M, Miura-Yura E, Zaghlool A, Evans MA, Fall T, De Hoyos HN, Sundström J, Yura Y, Kour A, Arai Y, Thel MC, Arai Y, Mychaleckyj JC, Hirschi KK, Forsberg LA, Walsh K. Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality. Science. 2022 Jul 15;377(6603):292-297.

Chavkin NW, Min KD, Walsh K. Importance of clonal hematopoiesis in heart failure. Trends Cardiovasc Med. 2022 May;32(4):198-203.

2021

Chavkin NW#, Cain S, Walsh K, Hirschi KK#. Isolation of Murine Retinal Endothelial Cells for Next-Generation Sequencing. J Vis Exp. 2021 Oct 11;(176):10.3791/63133. #Co-corresponding authors.

Chavkin NW*, Sano S*, Wang Y, Oshima K, Ogawa H, Horitani K, Sano M, MacLauchlan S, Nelson A, Setia K, Vippa T, Watanabe Y, Saucerman JJ, Hirschi KK, Gokce N, Walsh K. The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation. J Am Heart Assoc. 2021 Jul 6;10(13):e019904. *Co-first authors.

2020

Chavkin NW, Hirschi KK. Single Cell Analysis in Vascular Biology. Front Cardiovasc Med. 2020 Mar 31;7:42.